Rogaine is the trade name of minoxidil, which belongs to a class of drugs known as vasodilators. Rogaine is available in solution or foam dosage form, and it one of the top solutions in the management of male pattern baldness. Rogaine dilates blood vessels in the scalp hence improving the function of the hair follicle. The drug should be used continuously to maintain the regrowth of the hair.
The mechanism of Rogaine operation
Rogaine is known to boost the survival of human dermal papillary cells. The drugs act by activating the extracellular signal-regulated kinase (ERK) and the protein kinase B cells. Rogaine also prevents cell death by raising the ratio of BCl-/Bax. The drug stimulates the growth of human hairs by boosting anagen through its antiproliferative and antiapoptotic activities on the Death Presenting Cells. When administered as a vasodilator, Rogaine acts by opening potassium channels in the vascular smooth muscle cells. The vasodilation effect is thought to enhance the viability of the hair follicles.
Uses of Rogaine
Rogaine is employed in the management of male pattern baldness in men experiencing alopecia. Women experiencing thinning hair can also be treated using Rogaine. The drug is also used in the stabilization of hair loss in patients having androgenic alopecia. Minoxidil is also utilized in the treatment of high blood pressure in patients having severe hypertension.
Most individuals who use Rogaine rarely experience serious side effects. Doctors direct the use of this drug because its benefits are greater than its side effects. However, one may experience a burning or redness at the site of application. If the side effects persist for long, it is advisable to contact a pharmacist or a doctor for further directions.
Other rare side effects include allergic reactions that may present with a rash, itching, or swelling of the tongue or throat. The patient may also experience dizziness, drowsiness, and shortness of breath. The patient may also experience unwanted facial hairs, arrhythmias, fatigue and unusual weight gain.
Drug interactions associated with Rogaine
Interaction with other medications may change the efficacy of Rogaine. The result may be increased severe adverse reactions. Products that may interact with Rogaine include other antihypertensive medications such as guanethidine and drugs that interact with alcohol such as metronidazole and disulfiram. The patient should notify the health expert both the prescription and non-prescription medicines and herbal products.
Contraindications of Rogaine
The medication should not be utilized if the skin of the scalp is swollen, irritated or infected. The irritation on the skin may allow the medication to be absorbed by the body leading to unwanted effects. Patients suffering from a heart disease should inform the pharmacist or doctor before using the drug.
When one misses a dose of Rogaine, he/she should skip the missed and dose and continue with the usual dosing schedule. It is not recommendable to double the dose as this could lead to adverse effects.
Storage of Rogaine
The drug should be kept at room temperature. The product is flammable, and hence it should be stored away from a fire. After treatment, the patient should stay away from flames until the topical application has dried. Once the patient no longer needs the drug, it should be discarded properly by consulting the pharmacist or a waste disposal company for directions.